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Article

GPX Pro198Leu and OGG1 Ser326Cys polymorphisms and risk of development of colorectal adenomas and colorectal cancer.

Cancer letters - 8 Nov 2005

Hansen Rikke, Saebø Mona, Skjelbred Camilla Furu, Nexø Bjørn Andersen, Hagen Per Christian, Bock Günther, Bowitz Lothe Inger Marie, Johnson Egil, Aase Steinar, Hansteen Inger-Lise, Vogel Ulla, Kure Elin H

Abstract excerpt

Little is known about genetic risk factors for colorectal cancer. We assessed the association between polymorphisms in two genes involved in DNA repair of oxidative stress, GPX and OGG1, and risk of colorectal carcinoma or adenomas. We studied 166 cases with adenocarcinoma, 974 with adenomas and 397 controls recruited from the Norwegian cohort NORCCAP. No associations were found between the polymorphism GPX...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15946795
DOI: 10.1016/j.canlet.2005.04.019

Genes

OGG1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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GPX Pro198Leu and OGG1 Ser326Cys polymorphisms and risk of development of colorectal adenomas and colorectal cancer.PMID 15946795Read ↗

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Association of OGG1 Ser326Cys polymorphism with colorectal cancer risk: a meta-analysis.Semantic proximity Read ↗

The hOGG1 Ser326Cys polymorphism is not associated with colorectal cancer risk.Semantic proximity Read ↗

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No association of XRCC1 polymorphisms Arg194Trp and Arg399Gln with colorectal cancer risk.Semantic proximity Read ↗

DNA repair gene 8-oxoguanine DNA glycosylase Ser326Cys polymorphism and colorectal cancer risk in a Kashmiri population.Semantic proximity Read ↗

Role of the oxidative DNA damage repair gene OGG1 in colorectal tumorigenesis.Semantic proximity Read ↗

GPX1 Pro(198)Leu polymorphism, erythrocyte GPX activity, interaction with alcohol consumption and smoking, and risk of colorectal cancer.Semantic proximity Read ↗

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