Article
No association of XRCC1 polymorphisms Arg194Trp and Arg399Gln with colorectal cancer risk.
Cancer epidemiology - 1 Oct 2011
Gsur Andrea, Bernhart Kathrin, Baierl Andreas, Feik Elisabeth, Führlinger Gerhard, Hofer Philipp, Leeb Gernot, Mach Karl, Micksche Michael
Abstract excerpt
BACKGROUND: X-ray repair cross complementation group 1 (XRCC1) plays a key role in base excision repair. The purpose of this study was to examine the association of two genetic polymorphisms in XRCC1 (rs1799782 and rs25487) with risk of colorectal polyps and colorectal cancer (CRC). METHODS: In the ongoing colorectal cancer study of Austria (CORSA), a total of 3091 Caucasian participants was genotyped using...
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