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Article

DNA repair gene 8-oxoguanine DNA glycosylase Ser326Cys polymorphism and colorectal cancer risk in a Kashmiri population.

DNA and cell biology - 1 Apr 2012

Sameer A Syed, Nissar Saniya, Abdullah Safiya, Chowdri Nissar A, Siddiqi Mushtaq A

Abstract excerpt

8-Oxoguanine DNA glycosylase (OGG1) is one of the important base excision repair enzymes that repair 8-oxoguanine lesion incorporated within the DNA of an individual by reactive oxygen species. The aim of this study was to detect the role of OGG1 Ser326Cys polymorphism in susceptibility to colorectal cancer (CRC) in a Kashmiri population. We investigated the genotype distribution of the OGG1 gene in 114 CRC cases...

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Identifiers

PMID: 21899442
DOI: 10.1089/dna.2011.1349

Genes

OGG1

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DNA repair gene 8-oxoguanine DNA glycosylase Ser326Cys polymorphism and colorectal cancer risk in a Kashmiri population.PMID 21899442Read ↗

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