Article
Glutathione S-transferase P1 Ile105Val polymorphism and colorectal cancer risk: a meta-analysis and HuGE review.
European journal of cancer (Oxford, England : 1990) - 1 Dec 2009
Gao Yong, Pan Xiaofen, Su Ting, Mo Zengnan, Cao Yunfei, Gao Feng
Abstract excerpt
Colorectal cancer is the third most common form of cancer and the fourth most frequent cause of cancer deaths worldwide. Its development is influenced by both environmental and genetic factors. The glutathione S-transferase P1 gene (GSTP1) is a particularly attractive candidate for colorectal cancer susceptibility because it codes the enzyme involved in the metabolism of environmental carcinogens such as...
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