Association of OGG1 Ser326Cys polymorphism with colorectal cancer risk: a meta-analysis.

doi:10.1007/s00384-011-1258-9

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Article

Association of OGG1 Ser326Cys polymorphism with colorectal cancer risk: a meta-analysis.

International journal of colorectal disease - 1 Dec 2011

Zhang Ying, He Bang-Shun, Pan Yu-Qin, Xu Ye-Qiong, Wang Shu-Kui

Abstract excerpt

INTRODUCTION: 8-Oxoguanine DNA glycosylase 1 (OGG1), a key protein involved in the base excision repair pathway, can recognize and excise several lesions from oligodeoxynucleotides with single DNA damage. A C/G polymorphism at 1,245 bp (C1245G) in exon 7 of the OGG1 (Ser326Cys, rs1052133) is found to have a lower enzymatic activity. A variety of case-control studies have been published evaluating the association...

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Identifiers

PMID: 21695387
DOI: 10.1007/s00384-011-1258-9

Genes

OGG1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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