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Article

Contribution of common monoallelic MUTYH gene variants in German patients with familial colorectal cancer.

Cancer biomarkers : section A of Disease markers - 1 Jan 2008

Grünhage Frank, Jungck Matthias, Lamberti Christof, Schulte-Witte Hildegard, Plassmann Dominik, Becker Ursula, Rahner Nils, Aretz Stefan, Friedrichs Nicolaus, Buettner Reinhard, Sauerbruch Tilman, Lammert Frank

Abstract excerpt

UNLABELLED: Mutations of the base excision repair gene MUTYH have been reported as underlying genetic defects in autosomal-recessive familial adenomatous polyposis (FAP). Our aim was to determine the frequency of the most common mutations (p.Tyr165Cys and p.Gly382Asp) in patients with strong evid...

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Source

Identifiers

PMID: 18503156
DOI: 10.3233/cbm-2008-4201

Genes

MUTYH
FAP
MLH1
MSH2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18503156-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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