Article
Polymorphisms in signal transducer and activator of transcription 3 and lung function in asthma.
Respiratory research - 3 Jun 2005
Litonjua Augusto A, Tantisira Kelan G, Lake Stephen, Lazarus Ross, Richter Brent G, Gabriel Stacey, Silverman Eric S, Weiss Scott T
Abstract excerpt
BACKGROUND: Identifying genetic determinants for lung function is important in providing insight into the pathophysiology of asthma. Signal transducer and activator of transcription 3 is a transcription factor latent in the cytoplasm; the gene (STAT3) is activated by a wide range of cytokines, and may play a role in lung development and asthma pathogenesis. METHODS: We genotyped six single nucleotide...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
