The effect of overdominance on characterizing deleterious mutations in large natural populations.

doi:10.1093/genetics/151.2.895

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Article

The effect of overdominance on characterizing deleterious mutations in large natural populations.

Genetics - 1 Feb 1999

Li J L, Li J, Deng H W

Abstract excerpt

Alternatives to the mutation-accumulation approach have been developed to characterize deleterious genomic mutations. However, they all depend on the assumption that the standing genetic variation in natural populations is solely due to mutation-selection (M-S) balance and therefore that overdomi...

Topics

Animals
Genes, Dominant
Genetics, Population
Humans
Models, Genetic
Mutation

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