Article
Upper limit of the rate and per generation effects of deleterious genomic mutations.
Genetical research - 1 Aug 2006
Deng Hong-Wen, Li Jian, Pfrender Michael E, Li Jin-Long, Deng Hongyi
Abstract excerpt
Unbiased or upper limit estimates of the rate (U) of genomic mutations to mildly deleterious alleles are crucial in genetic and conservation studies and in human health care. However, only a few estimates of the lower bounds of U are available. We present a fairly robust estimation that yields an...
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