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Article

Mei1 is epistatic to Dmc1 during mouse meiosis.

Chromosoma - 1 Jul 2005

Reinholdt Laura G, Schimenti John C

Abstract excerpt

The Mei1(m1Jcs) allele contains a point mutation in a novel gene required for normal meiosis in male and female mice. We previously hypothesized that Mei1 is likely required for the formation of genetically programmed double-strand breaks (DSBs), the initiating event of meiotic recombination because in mutant spermatocytes (1) RAD51 foci are greatly reduced at zygonema; (2) RAD51 foci can be restored by...

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Source

Identifiers

PMID: 15928951
DOI: 10.1007/s00412-005-0346-4

Genes

RAD51
DMC1
MEI1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Mei1 is epistatic to Dmc1 during mouse meiosis.PMID 15928951Read ↗

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