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From meiosis to postmeiotic events: Uncovering the molecular roles of the meiosis‐specific recombinase Dmc1

15 Dec 2009

Abstract excerpt

In meiosis, the accurate segregation of maternal and paternal chromosomes is accomplished by homologous recombination. A central player in meiotic recombination is the Dmc1 recombinase, a member of the RecA/Rad51 recombinase superfamily, which is widely conserved from viruses to humans. Dmc1 is a meiosis-specific protein that functions with the ubiquitously expressed homolog, the Rad51 recombinase, which is...

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PMID: 20015079
DOI: 10.1111/j.1742-4658.2009.07503.x

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Related research

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From meiosis to postmeiotic events: Uncovering the molecular roles of the meiosis‐specific recombinase Dmc1PMID 20015079Read ↗

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The mouse RecA-like gene Dmc1 is required for homologous chromosome synapsis during meiosis.Semantic proximity Read ↗

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The FLIP-FIGNL1 complex regulates the dissociation of RAD51/DMC1 in homologous recombination and replication fork restartSemantic proximity Read ↗

RAD51 supports DMC1 by inhibiting the SMC5/6 complex during meiosis.Semantic proximity Read ↗

Interhomolog bias during meiotic recombination: meiotic functions promote a highly differentiated interhomolog-only pathway.Semantic proximity Read ↗

The fission yeast FANCM ortholog directs non-crossover recombination during meiosis.Semantic proximity Read ↗

DMC1 functions in a Saccharomyces cerevisiae meiotic pathway that is largely independent of the RAD51 pathway.Semantic proximity Read ↗

Genetic control of meiosis surveillance mechanisms in mammalsSemantic proximity Read ↗

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