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Article

Disruption of dmc1 Produces Abnormal Sperm in Medaka (Oryzias latipes)

2 Aug 2016

Abstract excerpt

DMC1 is a recombinase that is essential for meiotic synapsis. Experiments in extensive species of eukaryotes have indicated the independent role of DMC1 in repairing double strand breaks (DSBs) produced during meiosis I. Mutation of dmc1 in mice and human often leads to obstacles in spermatogenesis and male sterility. Here, we report on the disruption of dmc1 in male medaka (Oryzias latipes). Synapsis was...

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PMID: 27480068
DOI: 10.1038/srep30912

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