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Article

DDR complex facilitates global association of RNA polymerase V to promoters and evolutionarily young transposons.

Nature structural & molecular biology - 1 Sept 2012

Zhong Xuehua, Hale Christopher J, Law Julie A, Johnson Lianna M, Feng Suhua, Tu Andy, Jacobsen Steven E

Abstract excerpt

The plant-specific DNA-dependent RNA polymerase V (Pol V) evolved from Pol II to function in an RNA-directed DNA methylation pathway. Here, we have identified targets of Pol V in Arabidopsis thaliana on a genome-wide scale using ChIP-seq of NRPE1, the largest catalytic subunit of Pol V. We found that Pol V is enriched at promoters and evolutionarily recent transposons. This localization pattern is highly...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22864289
DOI: 10.1038/nsmb.2354
PMCID: PMC3443314

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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DDR complex facilitates global association of RNA polymerase V to promoters and evolutionarily young transposons.PMID 22864289Read ↗

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