Article
The Second Subunit of DNA Polymerase Delta Is Required for Genomic Stability and Epigenetic Regulation.
Plant physiology - 1 Jun 2016
Zhang Jixiang, Xie Shaojun, Cheng Jinkui, Lai Jinsheng, Zhu Jian-Kang, Gong Zhizhong
Abstract excerpt
DNA polymerase δ plays crucial roles in DNA repair and replication as well as maintaining genomic stability. However, the function of POLD2, the second small subunit of DNA polymerase δ, has not been characterized yet in Arabidopsis (Arabidopsis thaliana). During a genetic screen for release of transcriptional gene silencing, we identified a mutation in POLD2. Whole-genome bisulfite sequencing indicated that...
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