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Article

Dissection of the Drosophila paired protein: functional requirements for conserved motifs.

Mechanisms of development - 1 Aug 1994

Cai J, Lan Y, Appel L F, Weir M

Abstract excerpt

The Drosophila paired gene encodes three conserved motifs: a homeodomain, paired domain and PRD (his/pro) repeat. To investigate the functional importance of the PRD repeat and paired domain, we tested deletion mutants using an ectopic expression assay in embryos. Our results suggest that the PRD repeat is not required for the in vivo regulation of the target genes, engrailed and gooseberry. However, the PRD...

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Identifiers

PMID: 7811637
DOI: 10.1016/0925-4773(94)90086-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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