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Article

Identification of residues of the Caenorhabditis elegans LIN-1 ETS domain that are necessary for DNA binding and regulation of vulval cell fates.

Genetics - 1 Aug 2004

Miley Ginger R, Fantz Douglas, Glossip Danielle, Lu Xiaowei, Saito R Mako, Palmer Robert E, Inoue Takao, Van Den Heuvel Sander, Sternberg Paul W, Kornfeld Kerry

Abstract excerpt

LIN-1 is an ETS domain protein. A receptor tyrosine kinase/Ras/mitogen-activated protein kinase signaling pathway regulates LIN-1 in the P6.p cell to induce the primary vulval cell fate during Caenorhabditis elegans development. We identified 23 lin-1 loss-of-function mutations by conducting several genetic screens. We characterized the molecular lesions in these lin-1 alleles and in several previously identified...

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Identifiers

PMID: 15342509
DOI: 10.1534/genetics.104.029017
PMCID: PMC1471005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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