Article
Differential expression of p63 isoforms in female reproductive organs.
Mechanisms of development - 1 Sept 2005
Kurita Takeshi, Cunha Gerald R, Robboy Stanley J, Mills Alea A, Medina Roanna T
Abstract excerpt
p63 is the identity switch for uterine/vaginal epithelial cell fate, and disruption of p63 expression by diethylstilbestrol (DES) induces cervical/vaginal adenosis in mice. In this article, we report the expression patterns of p63 isoforms (TA, DeltaN, alpha, beta and gamma) in mice, focusing on the reproductive tract. We also present the reproductive tract phenotype of female p63-/- mice. Finally, to better...
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