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Article

p63 (TP73L) a key player in embryonic urogential development with significant dysregulation in human bladder exstrophy tissue

21 Oct 2010

Abstract excerpt

Human bladder exstrophy-epispadias complex (BEEC) comprises a spectrum of urogenital anomalies in which part or all of the distal urinary tract fails to close. Several lines of evidence implicate genetic factors in the formation of BEEC. Among them a murine p63+/+ knockout model showed the full picture of classic exstrophy of the bladder and other urogenital defects within the BEEC spectrum. This led us to study...

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Share to Bladder and Urothelial Cancer Treatments
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Identifiers

PMID: 21042780
DOI: 10.3892/ijmm_00000535

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Related research

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p63 (TP73L) a key player in embryonic urogential development with significant dysregulation in human bladder exstrophy tissuePMID 21042780Read ↗

Candidate gene association study implicates p63 in the etiology of nonsyndromic bladder-exstrophy-epispadias complex.Semantic proximity Read ↗

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No TAP63 promoter mutation is detected in bladder exstrophy-epispadias complex patients.Semantic proximity Read ↗

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