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Taking Advantage of Basic Research: p63 Is a Reliable Myoepithelial and Stem Cell Marker

1 Sept 2002

Abstract excerpt

p63 is a recently characterized p53-homolog that is consistently expressed by basal/somatic stem cells of stratified epithelia, myoepithelial cells of the breast and salivary glands, and proliferative compartment of gastric mucosa. p63 is located on the long arm of chromosome 3 (3q27) and it encodes six isoforms, three transactivating (TA) and three DeltaN-isoforms. While the first three isoforms may act as tumor...

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PMID: 12195217
DOI: 10.1097/00125480-200209000-00002

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