Human serum paraoxonase.

doi:10.1016/s0306-3623(98)00028-7

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Article

Human serum paraoxonase.

General pharmacology - 1 Sept 1998

Mackness B, Durrington P N, Mackness M I

Abstract excerpt

1. Human serum paraoxonase (PON1) is a Ca2+-dependent 45-kDa glycoprotein that is associated with high density lipoprotein (HDL). 2. PON1 hydrolyzes organophosphate (OP) insecticides and nerve gases and is responsible for determining the selective toxicity of these compounds in mammals. 3. PON1 h...

Topics

Arteriosclerosis
Aryldialkylphosphatase
Esterases
Genotype
Glycoproteins
Humans
Lipoproteins, HDL
Organophosphorus Compounds
Polymorphism, Genetic

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