Article
Frequency of paraoxonase 192/55 polymorphism in an Iranian population.
Journal of toxicology and environmental health. Part A - 1 Jul 2007
Sepahvand Farideh, Rahimi-Moghaddam Parvaneh, Shafiei Massoumeh, Ghaffari Seyed Mahmood, Rostam-Shirazi Mehran, Mahmoudian Massoud
Abstract excerpt
Paraoxonase (PON1) is a serum enzyme that plays an important role in prevention of atherosclerosis and also protects against organophosphate-induced neurotoxicity. PON1 displays a high variability in human populations. In this study, PON1-192 and -55 polymorphisms and correlation to serum PON1 activity were investigated in 132 healthy Iranian individuals from Isfahan province. The genotype frequencies for...
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