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Article

Vascular respiratory uncoupling increases blood pressure and atherosclerosis.

Nature - 26 May 2005

Bernal-Mizrachi Carlos, Gates Allison C, Weng Sherry, Imamura Takuji, Knutsen Russell H, DeSantis Pascual, Coleman Trey, Townsend R Reid, Muglia Louis J, Semenkovich Clay F

Abstract excerpt

The observations that atherosclerosis often occurs in non-smokers without elevated levels of low-density lipoprotein cholesterol, and that most atherosclerosis loci so far identified in mice do not affect systemic risk factors associated with atherosclerosis, suggest that as-yet-unidentified mechanisms must contribute to vascular disease. Arterial walls undergo regional disturbances of metabolism that include the...

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Identifiers

PMID: 15917810
DOI: 10.1038/nature03527

Genes

UCP1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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