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<i>OCT‐4</i>, an embryonic stem cell marker, is highly expressed in bladder cancer

4 Jan 2007

Abstract excerpt

OCT-4 (also known as POU5F1) is a key regulator of self-renewal in embryonic stem cells. Regarding the new cancer stem cell concept, the expression of such genes is potentially correlated with tumorigenesis and can affect some aspects of tumor behavior, such as tumor recurrence or resistance to therapies. Although OCT-4 has been introduced as a molecular marker for germ cell tumors, little is known about its...

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PMID: 17205510
DOI: 10.1002/ijc.22508

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