Article
No association between microsomal triglyceride transfer protein (MTP) haplotype and longevity in humans.
Proceedings of the National Academy of Sciences of the United States of America - 31 May 2005
Nebel Almut, Croucher Peter J P, Stiegeler Rieke, Nikolaus Susanna, Krawczak Michael, Schreiber Stefan
Abstract excerpt
Human longevity is a multifactorial condition with a significant genetic contribution. A recent association study in two independent samples of long-lived U.S. Caucasians [long-lived individuals (LLI)] identified a SNP haplotype of the microsomal triglyceride transfer protein (MTP, 4q25) that was underrepresented among LLI when compared with younger controls. This suggested that variation in the MTP gene might...
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