Article
Absence of relationship between MTTP haplotypes and longevity.
The journals of gerontology. Series A, Biological sciences and medical sciences - 1 Feb 2007
Neville Matt J, Clarke Robert, Evans John Grimley, Rubinsztein David C, Karpe Fredrik
Abstract excerpt
BACKGROUND: Polymorphisms for the microsomal triglyceride transfer protein (MTTP) gene have been associated with longevity and with lower risk for cardiovascular mortality. However, the association of MTTP with longevity has been contested in a large German collection of nonagenarians and centenarians. METHODS: We made a detailed characterization of MTTP haplotype carrier status in a cohort of 1398 old men and...
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