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Article

Human longevity and common variations in the LMNA gene: a meta-analysis.

Aging cell - 1 Jun 2012

Conneely Karen N, Capell Brian C, Erdos Michael R, Sebastiani Paola, Solovieff Nadia, Swift Amy J, Baldwin Clinton T, Budagov Temuri, Barzilai Nir, Atzmon Gil, Puca Annibale A, Perls Thomas T, Geesaman Bard J, Boehnke Michael, Collins Francis S

Abstract excerpt

A mutation in the LMNA gene is responsible for the most dramatic form of premature aging, Hutchinson-Gilford progeria syndrome (HGPS). Several recent studies have suggested that protein products of this gene might have a role in normal physiological cellular senescence. To explore further LMNA's...

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Identifiers

PMID: 22340368
DOI: 10.1111/j.1474-9726.2012.00808.x
PMCID: PMC3350595

Genes

LMNA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22340368-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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