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Article

Haplotype-based identification of a microsomal transfer protein marker associated with the human lifespan.

Proceedings of the National Academy of Sciences of the United States of America - 25 Nov 2003

Geesaman Bard J, Benson Erica, Brewster Stephanie J, Kunkel Louis M, Blanché Hélène, Thomas Gilles, Perls Thomas T, Daly Mark J, Puca Annibale A

Abstract excerpt

We previously reported a genomewide linkage study for human longevity using 308 long-lived individuals (LLI) (centenarians or near-centenarians) in 137 sibships and identified statistically significant linkage within chromosome 4 near microsatellite D4S1564. This interval spans 12 million bp and contains approximately 50 putative genes. To identify the specific gene and gene variants impacting lifespan, we...

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Identifiers

PMID: 14615589
DOI: 10.1073/pnas.1936249100
PMCID: PMC283555

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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