Article
Absence of association between genetic variation in the promoter of the microsomal triglyceride transfer protein gene and plasma lipoproteins in the Framingham Offspring Study.
Atherosclerosis - 1 Feb 2000
Couture P, Otvos J D, Cupples L A, Wilson P W, Schaefer E J, Ordovas J M
Abstract excerpt
Microsomal triglyceride transfer protein (MTP) is a lipid transfer protein that is required for the assembly and secretion of very low density lipoproteins (VLDL) by the liver and chylomicrons by the intestine. The common G-493T polymorphism of the MTP promoter has been shown to be associated with decreased plasma LDL-cholesterol and ApoB content of VLDL. The purpose of the present study was, therefore, to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.