Article
Microsomal triglyceride transfer protein gene polymorphism strongly influences circulating malondialdehyde-modified low-density lipoprotein.
Metabolism: clinical and experimental - 1 Sept 2009
Okumura Kenji, Imamura Akiko, Murakami Ryuichiro, Takahashi Ryotaro, Cheng Xian Wu, Numaguchi Yasushi, Murohara Toyoaki
Abstract excerpt
Microsomal triglyceride transfer protein (MTP) plays a critical role in the assembly of lipoproteins. Therefore, we studied whether MTP gene polymorphisms are associated with atherosclerosis-promoting parameters, especially metabolic profiles and endothelial function, in healthy young men. One hundred one healthy men (mean age, 30.3 years) were studied. We analyzed the 2 promoter polymorphisms (-493G/T and...
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