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Article

Lack of association between IDE genetic variability and Down's syndrome.

Neuroscience letters - 1 Jan 2000

Arpino Carla, Piciullo Antonella, Palmarino Mariella, Saccucci Patrizia, Galasso Cinzia, Lucarelli Paola, Curatolo Paolo

Abstract excerpt

Virtually all patients with Down's syndrome develop Alzheimer disease (AD) during their life; thus, it is extremely important to investigate potential determinants of AD in this population. Previous studies found an association of DS with -48C/T presenilin-1 and with the -850 tumor necrosis factor-alpha, two polymorphisms of genes involved in amyloid beta modulation In this study, we evaluated whether the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15911128
DOI: 10.1016/j.neulet.2005.02.058

Genes

IDE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Lack of association between IDE genetic variability and Down's syndrome.PMID 15911128Read ↗

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