Article
Evidence on DNA slippage step-length distribution.
Physical review. E, Statistical, nonlinear, and soft matter physics - 1 Mar 2005
Borstnik Branko, Pumpernik Danilo
Abstract excerpt
A simple model based on a master equation is constructed in order to reveal the details of the mutational events modifying simple sequence repeats in the human genome, A database of simple repeats together with their flanking sequences comprising approximately 10(5) entries from all 24 human chromosomes was constructed. By aligning the pairs of fragments of sequences containing the repeat elements, the matrices...
Topics
- Chromosomes, Human
- DNA
- DNA Mutational Analysis
- Evidence-Based Medicine
- Evolution, Molecular
- Genetic Variation
- Genome, Human
- Humans
- Models, Chemical
- Models, Genetic
- Mutation
- Repetitive Sequences, Nucleic Acid
