Article
A law of mutation: power decay of small insertions and small deletions associated with human diseases.
Applied biochemistry and biotechnology - 1 Sept 2010
Zhang Jia, Xiao Li, Yin Yufang, Sirois Pierre, Gao Hanlin, Li Kai
Abstract excerpt
Indels in evolutionary studies are rapidly decayed obeying a power law. The present study analyzed the length distribution of small insertions and deletions associated with human diseases and confirmed that the decay pattern of these small mutations is similar to that of indels when the mutation datasets are large enough. The describable decay pattern of somatic mutations may have application in the evaluation of...
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