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Article

DNA slippage occurs at microsatellite loci without minimal threshold length in humans: a comparative genomic approach.

Genome biology and evolution - 12 Jul 2010

Leclercq Sébastien, Rivals Eric, Jarne Philippe

Abstract excerpt

The dynamics of microsatellite, or short tandem repeats (STRs), is well documented for long, polymorphic loci, but much less is known for shorter ones. For example, the issue of a minimum threshold length for DNA slippage remains contentious. Model-fitting methods have generally concluded that slippage only occurs over a threshold length of about eight nucleotides, in contradiction with some direct observations...

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PMID: 20624737
DOI: 10.1093/gbe/evq023
PMCID: PMC2997547

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