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Article

Reproductive and neurological Quaking(viable) phenotypes in a severe combined immune deficient mouse background.

Immunogenetics - 1 May 2005

Tucker Tammy A, Kundert Jean A, Bondareva Alla A, Schmidt Edward E

Abstract excerpt

The quaking(viable) (qkv) mutation, a spontaneous deletion of a multigenic region encompassing roughly 1 Mb at 5.9 cM on the proximal end of mouse chromosome 17, causes severe trembling in all homozygous animals and infertility in all homozygous males. Physiologically, quaking mice exhibit dysmyelination and postmeiotic spermatogenic arrest. Molecular defects in Qkv mice occur in the affected tissues, indicating...

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Identifiers

PMID: 15900494
DOI: 10.1007/s00251-005-0792-4
PMCID: PMC2604809

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Reproductive and neurological Quaking(viable) phenotypes in a severe combined immune deficient mouse background.PMID 15900494Read ↗

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Deletion of the Parkin coregulated gene causes male sterility in the quaking(viable) mouse mutant.Semantic proximity Read ↗

Quaking*shiverer double-mutant mice survive for at least 100 days with no CNS myelin.Semantic proximity Read ↗

Loss of p53 in quaking viable mice leads to Purkinje cell defects and reduced survival.Semantic proximity Read ↗

Defining the breakpoints of the quaking(viable) mouse mutation reveals a duplication from a Parkin intron.Semantic proximity Read ↗

Pleiotropic action of the murine quaking locus: structure of the qkv allele.Semantic proximity Read ↗

Protection of p27(Kip1) mRNA by quaking RNA binding proteins promotes oligodendrocyte differentiation.Semantic proximity Read ↗

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