Article
Pleiotropic action of the murine quaking locus: structure of the qkv allele.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jan 1991
King T R, Dove W F
Abstract excerpt
The spontaneous allele quakingviable (qkv) exerts effects on myelination and spermiogenesis. The defects generated by qkv were not separated in a multilocus mapping cross that provided a mapping resolution of 0.1 centiMorgans (cM). Furthermore, no distortions suggestive of a large chromosomal anomaly associated with qkv were apparent. One plausible interpretation is that the quaking locus contains more than one...
Topics
- Animals
- Chromosome Mapping
- DNA Transposable Elements
- Embryonic and Fetal Development
- Genetic Linkage
- Male
- Mice
- Mice, Inbred Strains
- Mice, Quaking
- Mutation
- Myelin Sheath