Article
Haplotype tag single nucleotide polymorphism analysis of the human orthologues of the rat type 1 diabetes genes Ian4 (Lyp/Iddm1) and Cblb.
Diabetes - 1 Feb 2004
Payne Felicity, Smyth Deborah J, Pask Rebecca, Barratt Bryan J, Cooper Jason D, Twells Rebecca C J, Walker Neil M, Lam Alex C, Smink Luc J, Nutland Sarah, Rance Helen E, Todd John A
Abstract excerpt
The diabetes-prone BioBreeding (BB) and Komeda diabetes-prone (KDP) rats are both spontaneous animal models of human autoimmune, T-cell-associated type 1 diabetes. Both resemble the human disease, and consequently, susceptibility genes for diabetes found in these two strains can be considered as...
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