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Article

Glutathione S-transferase gene polymorphisms in presbycusis.

Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology - 1 May 2005

Ateş Nurcan Aras, Unal Murat, Tamer Lülüfer, Derici Ebru, Karakaş Sevim, Ercan Bahadir, Pata Yavuz Selim, Akbaş Yücel, Vayisoğlu Yusuf, Camdeviren Handan

Abstract excerpt

HYPOTHESIS: Glutathione and glutathione-related antioxidant enzymes are involved in the metabolism and detoxification of cytotoxic and carcinogenic compounds as well as reactive oxygen species. Reactive oxygen species generation occurs in prolonged relative hypoperfusion conditions such as in aging. The etiology of presbycusis is much less certain; however, a complex genetic cause is most likely. The effect of...

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Source

Identifiers

PMID: 15891640
DOI: 10.1097/01.mao.0000169774.23668.f1

Genes

GSTM1
GSTP1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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