Article
The influence of genetic variation in oxidative stress genes on human noise susceptibility.
Hearing research - 1 Apr 2005
Carlsson Per-Inge, Van Laer Lut, Borg Erik, Bondeson Marie-Louise, Thys Melissa, Fransen Erik, Van Camp Guy
Abstract excerpt
Noise induced hearing loss (NIHL) is a complex disease caused by an interaction between genetic and environmental factors. Damage in the cochlea as a result of noise exposure appears to be mediated by reactive oxygen species (ROS). To investigate whether genetic variation in the human protective antioxidant system is associated with high or low susceptibility to NIHL, genetic polymorphisms derived from genes...
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