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Article

Antioxidant enzymes, presbycusis, and ethnic variability.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery - 1 Aug 2010

Bared Anthony, Ouyang Xiaomei, Angeli Simon, Du Li Lin, Hoang Kimberly, Yan Denise, Liu Xue Zhong

Abstract excerpt

OBJECTIVE: A proposed mechanism for presbycusis is a significant increase in oxidative stress in the cochlea. The enzymes glutathione S-transferase (GST) and N-acetyltransferase (NAT) are two classes of antioxidant enzymes active in the cochlea. In this work, we sought to investigate the association of different polymorphisms of GSTM1, GSTT1, and NAT2 and presbycusis and analyze whether ethnicity has an effect in...

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Source

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Identifiers

PMID: 20647132
DOI: 10.1016/j.otohns.2010.03.024
PMCID: PMC2913419

Genes

GSTM1
GSTT1
NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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