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Article

Associations of GST Gene Polymorphisms and GST Enzyme Activity with the Development of Noise-Induced Hearing Loss in Chinese Han Males.

Public health genomics - 1 Jan 2024

Ji Fang, Zhang Jian, Ding Xiaowen, Rong Li, Liu Xiaodong, Yan Tenglong, Li Jue

Abstract excerpt

INTRODUCTION: In noise-induced hearing loss (NIHL), glutathione S-transferases (GSTs) play a pivotal role as antioxidants in cochlear protection. Nevertheless, the variability in population and environmental factors complicates the interpretation of research findings on the association among GST gene polymorphism, GST enzyme activity, and NIHL, leading to inconsistent results. To explore the potential correlation...

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PMID: 39476807
DOI: 10.1159/000541618

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