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Article

Polymorphisms in folate metabolism genes are associated with susceptibility to presbycusis.

Life sciences - 1 Mar 2018

Manche Santoshi Kumari, Jangala Madhavi, Dudekula Dinesh, Koralla Meganadh, Akka Jyothy

Abstract excerpt

AIM: Presbycusis or age related hearing loss is caused by several extrinsic and intrinsic factors that damage the auditory system. Gene polymorphisms in folate metabolism were found to play an important role in the etiology of presbycusis. The present study aimed to investigate the role of 5,10-methylenetetrahydrofolate reductase (MTHFR), methionine synthase (MTR) and thymidylate synthase (TYMS) gene...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29369772
DOI: 10.1016/j.lfs.2018.01.015

Genes

MTHFR
TYMS
MTR

Variants

rs180133
rs180133
rs180133

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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Polymorphisms in folate metabolism genes are associated with susceptibility to presbycusis.PMID 29369772Read ↗

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