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Article

Influence of glutathione s-transferase on the ototoxicity caused by aminoglycosides.

Brazilian journal of otorhinolaryngology - 1 Jan 2000

Palodetto Bruna, Postal Mariana, Grignoli Carlos Roberto Escrivão, Sartorato Edi Lúcia, Oliveira Camila Andréa de

Abstract excerpt

UNLABELLED: The process of hair cell damage and death as a result of exposure to noise and ototoxins seems to be mediated by reactive oxygen species. AIM: To investigate the relationship between genetic polymorphisms in the Glutathione S-transferase and the susceptibility to hearing loss induced by aminoglycosides. MATERIALS AND METHODS: Null genotypes were analyzed by multiplex-PCR in the DNA samples from 50...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20658008
PMCID: PMC9442161

Genes

GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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