Article
N-acetyltransferase 2 gene polymorphism and presbycusis.
The Laryngoscope - 1 Dec 2005
Unal Murat, Tamer Lülüfer, Doğruer Zeynep Nil, Yildirim Hatice, Vayisoğlu Yusuf, Camdeviren Handan
Abstract excerpt
OBJECTIVES/HYPOTHESIS: The enzyme of N-acetyltransferase (NAT) is involved in the metabolism and detoxification of cytotoxic and carcinogenic compounds as well as reactive oxygen species (ROS). The excessive amount of ROS generation occurs in the ageing inner ear. The exact etiopathogenesis of presbycusis is not known, but it is generally accepted that it is the result of series of insults, such as physiologic...
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