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Article

Involvement of p21ras in Xenopus mesoderm induction.

Nature - 21 May 1992

Whitman M, Melton D A

Abstract excerpt

During early vertebrate embryogenesis, mesoderm is specified by a signal emanating from prospective endoderm. This signal can respecify Xenopus prospective ectoderm as mesoderm, and can be mimicked by members of the fibroblast growth factor and transforming growth factor-beta families. In other systems, the p21c-ras proto-oncogene product has been implicated in signal transduction for various polypeptide growth...

Topics

Activins
Animals
Blastocyst
Embryo, Nonmammalian
Female
Fibroblast Growth Factor 2
Genes, Dominant
Genes, ras
Genetic Variation
Inhibins
Mesoderm
Microinjections

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Oocytes

Proto-Oncogene Proteins p21(ras)

RNA, Messenger

Xenopus laevis

Source

Identifiers

PMID: 1589022
DOI: 10.1038/357252a0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1589022-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Involvement of p21ras in Xenopus mesoderm induction.PMID 1589022Read ↗

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