Article
Involvement of p21ras in Xenopus mesoderm induction.
Nature - 21 May 1992
Whitman M, Melton D A
Abstract excerpt
During early vertebrate embryogenesis, mesoderm is specified by a signal emanating from prospective endoderm. This signal can respecify Xenopus prospective ectoderm as mesoderm, and can be mimicked by members of the fibroblast growth factor and transforming growth factor-beta families. In other systems, the p21c-ras proto-oncogene product has been implicated in signal transduction for various polypeptide growth...
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