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Article

Biological properties of human c-Ha-ras1 genes mutated at codon 12.

Nature - 1 Jan 2000

Seeburg P H, Colby W W, Capon D J, Goeddel D V, Levinson A D

Abstract excerpt

Vertebrate genomes contain proto-oncogenes whose enhanced expression or alteration by mutation seems to be involved in the development of naturally occurring tumours. These activated genes, usually assayed by their ability to induce the malignant transformation of NIH 3T3 cells, are frequently related to the ras oncogene of Harvey (Ha-ras) or Kirsten (Ki-ras) murine sarcoma viruses, or a third member of this...

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PMID: 6092966
DOI: 10.1038/312071a0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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