Article
Ras-mediated FGF signaling is required for the formation of posterior but not anterior neural tissue in Xenopus laevis.
Developmental biology - 1 Nov 2000
Ribisi S, Mariani F V, Aamar E, Lamb T M, Frank D, Harland R M
Abstract excerpt
Fibroblast growth factor (FGF) has been proposed to be involved in the specification and patterning of the developing vertebrate nervous system. There is conflicting evidence, however, concerning the requirement for FGF signaling in these processes. To provide insight into the signaling mechanisms that are important for neural induction and anterior-posterior neural patterning, we have employed the dominant...
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