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Article

Targeted gene deletion in Candida albicans wild-type strains by MPAR flipping.

Methods in molecular medicine - 1 Jan 2005

Morschhäuser Joachim, Staib Peter, Köhler Gerwald

Abstract excerpt

Many genetic and phenotypic changes occur during the development of drug resistance in fungi. A straightforward approach to assess the contribution of a specific gene to drug resistance is to examine its inactivation in a resistant isolate and to analyze the effect of the mutation on the resistance phenotype. The generation of knockout mutants in the diploid yeast Candida albicans requires two rounds of gene...

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Share to Candida albicans
Share to Drug Resistance, Fungal
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Gene Targeting

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Share to Mutagenesis, Insertional

Share to Transformation, Genetic

Source

Identifiers

PMID: 15888933
DOI: 10.1385/1-59259-943-5:035

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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