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Article

A new rapid and efficient system with dominant selection developed to inactivate and conditionally express genes in Candida albicans.

Current genetics - 1 Feb 2016

Lai Wei-Chung, Sun Hsiao-Fang Sunny, Lin Pei-Hsuan, Ho Lin Ho Lin, Shieh Jia-Ching

Abstract excerpt

Candida albicans is an important human fungal pathogen but its study has been hampered for being a natural diploid that lacks a complete sexual cycle. Gene knock-out and essential gene repression are used to study gene function in C. albicans. To effectively study essential genes in wild-type C. albicans, we took advantage of the compatible effects of the antibiotics hygromycin B and nourseothricin, the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26497136
DOI: 10.1007/s00294-015-0526-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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