Article
Going green in Cryptococcus neoformans: the recycling of a selectable drug marker.
Fungal genetics and biology : FG & B - 1 Mar 2010
Patel Raunak D, Lodge Jennifer K, Baker Lorina G
Abstract excerpt
Cryptococcus neoformans is an opportunistic fungal pathogen that primarily affects immunocompromised individuals. Reverse genetics is commonly used to identify and characterize genes involved in a variety of cellular processes. In C. neoformans there is a limited set of positive selectable markers available to make gene deletions or other genetic manipulations. This has hampered the application of reverse...
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