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Article

PAI-1 gene 4G/5G polymorphism, cytokine levels and their relations with metabolic parameters in obese children.

Thrombosis and haemostasis - 1 Feb 2008

Kinik Sibel Tulgar, Ozbek Namik, Yuce Muammer, Yazici Ayse Canan, Verdi Hasibe, Ataç F Belgin

Abstract excerpt

Obesity is associated with the changes of plasminogen activator inhibitor-1 (PAI-1), tumor necrosis factor-alpha (TNFalpha) and transforming growth factor beta (TGFbeta) levels. However, the precise effect of the 4G allele on obesity is still contradictory. Here, we aimed to elucidate the role of the 4G/5G polymorphism of the PAI-1 gene on the PAI-1 level and determine the associations between cytokines, glucose...

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Identifiers

PMID: 18278185
DOI: 10.1160/TH07-06-0395

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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